In February 2016, the World Health Organization declared Zika virus outbreak in Latin America and other areas a public health emergency of international concern, because Zika virus can cause birth defects and neurological problems. Since then, Zika virus has been a topic of concern in the news media. Although a sensational topic, the reality is that Zika is a mosquito-borne virus that causes no illness in some people, and mild to moderate illness in others, lasting about a week; the vast majority of those infected with Zika virus do not become seriously ill. However, Zika virus has been shown to cause serious birth defects in children born to infected mothers. It also has been linked to the neurological disorder Guillain-Barré Syndrome in some people. This course discusses the discovery, transmission, symptoms, diagnoses, treatment, risks, and prevention of Zika virus.